Feudal Future Podcast — COVID mRNA Vaccines and the State of Future Pandemics

On today's episode of Feudal Future hosts Joel Kotkin and Marshall Toplansky are joined by guests Joe Payne and Tony Lemus. Joseph E. Payne is the President and Chief Executive Officer of Arcturus Therapeutics. Arcturus therapeutics is a leading clinical-stage messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics for rare diseases and vaccines.

Their conversation begins with Marshall asking Joe about different vaccines that are being approved rapidly and how they are receiving emergency permits for the market. Joe breaks down scientifically how mRNA works with the body and how the results look promising for covid19. Arcturus is in the middle of phase 1 and 2 trials with over 100 participants. Joe continued, highlighting that their vaccine could be a single dose vaccine as well as a low dosage.

Tony joined the conversation and added that the predictive models, coupled with the clinical trials, using AI, has sped the process of approval and are able to leap-frog the FDA with less red tape.

Joel brought up a problem. If multiple vaccines come out, which ones will be the best? Joe states that efficacy is the current issue, but the conversation will shift to convenience; cost and single administration. Joel continues and asks if this vaccine will stop the wave of pandemics due to the virus. Joe states that COVID-19 is here to stay regardless of the vaccine and that it will take time for herd immunity to develop.

As the episode ends, Joe explains how the beauty of mRNA vaccines is through a non-viral delivery and how this vaccine will be the benchmark for future pandemics.

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Leran about Joel's book, The Coming of Neo-Feudalism.